课程概述

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1...

Oct 1, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

May 19, 2020

This course was new to me. All the concepts were explained in a very simplified manner. I am very happy to have done this course and find it a very interesting field to take upm in my future career.

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学生对 墨尔本大学 提供的 基因表达的表观遗传调控 的评价和反馈

课程概述

热门审阅

151 - 基因表达的表观遗传调控 的 175 个评论（共 194 个）

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热门在线课程

热门在线专项课程

在线证书

在线学位课程

Coursera

社区

更多

学生对墨尔本大学提供的基因表达的表观遗传调控的评价和反馈

151 - 基因表达的表观遗传调控的 175 个评论（共 194 个）