About this course: You have all heard about the DNA double helix and genes. Many of you know that mutations occur randomly, that the DNA sequence is read by successive groups of three bases (the codons), that many genes encode enzymes, and that gene expression can be regulated. These concepts were proposed on the basis of astute genetic experiments, as well as often on biochemical results. The original articles were these concepts appeared are however not frequently part of the normal curriculum of biologists, biochemists and medical students. This course proposes to read study and discuss a small selection of these classical papers, and to put these landmarks in their historical context. Most of the authors displayed interesting personal histories and many of their contributions go beyond not only the papers we will read but probably all their scientific papers. Our understanding of the scientific process, of the philosophy underlying the process of scientific discovery, and on the integration of new concepts is not only important for the history of science but also for the mental development of creative science.
Taught by: Dominique Belin, Professor
Department of Pathology and Immunology University of Geneva Medical School
| Language | English |
| How To Pass | Pass all graded assignments to complete the course. |
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Very interesting topics! Gave me a new perspective on things. It's easy to take for granted the amount of knowledge we have know. This course puts things into perspective. I have also learned values which could help me in my career as a scientist.
A historical vision on molecular genetics taken from the original papers. Two important facts of this excellent course are: 1) the description of all the stories surrounding the lives of the researchers at the time of performing the experiments; and 2: the detailed analyses of the papers commented by Professor Dominique Belin pointing out the crucial point to be taken into account. I consider that Professor Belin is a great teacher.
Best course I've taken on Coursera so far. The sessions are challenging but manageable with only a quiz due at each week. I loved how each lesson covered not only science, but history, relationships, quirks among scientists, and other fun facts of early molecular genetic experiments and scientists. The professor is a very good presenter, engaging, and makes the topics even more intriguing.
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Through this course you will be able to understand (and appreciate) better many things of the day-to-day work as a molecular biologist. This course offers you a very detailed description of scientific and social aspects behind key discoveries in the field. Professor Belin classes remind me of SJ Gould readings. So far, the best class in coursera.