This course familiarizes students with the novel concepts being used to revamp regulatory toxicology in response to a breakthrough National Research Council Report “Toxicity Testing in the 21st Century: A Vision and a Strategy.” We present the latest developments in the field of toxicology—the shift from animal testing toward human relevant, high content, high-throughput integrative testing strategies. Active programs from EPA, NIH, and the global scientific community illustrate the dynamics of safety sciences.
提供方
Toxicology 21: Scientific Applications
约翰霍普金斯大学课程信息
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中级
完成时间大约为96 小时
英语（English）
字幕：法语（French）, （欧洲人讲的）葡萄牙语, 俄语（Russian）, 英语（English）, 西班牙语（Spanish）
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体验 Coursera 企业版可灵活调整截止日期
根据您的日程表重置截止日期。
可分享的证书
完成后获得证书
100% 在线
立即开始，按照自己的计划学习。
中级
完成时间大约为96 小时
英语（English）
字幕：法语（French）, （欧洲人讲的）葡萄牙语, 俄语（Russian）, 英语（English）, 西班牙语（Spanish）
对员工进行热门技能培训能否为您的公司带来益处？
体验 Coursera 企业版
提供方
约翰霍普金斯大学
The mission of The Johns Hopkins University is to educate its students and cultivate their capacity for life-long learning, to foster independent and original research, and to bring the benefits of discovery to the world.
授课大纲 - 您将从这门课程中学到什么
完成时间为 75 小时
Module 1
This model will give you a broad introduction to the Toxicology 21st century (Tox21c) field and familiarize you with the main document, which summarize the main ideas and principles of Tox21c.
完成时间为 75 小时
10 个视频 （总计 121 分钟）, 3 个阅读材料, 1 个测验
完成时间为 4 小时
Module 2
This module will discuss how ToxCast and Tox21 technologies can be used in practice. The US EPA Endocrine Disruptor Screening Program will be discussed in detail and we will demonstrate how the ToxCast platform replaced in vivo tiered approaches in EDSP and, thus, acelerate the process of . In the second lesson of this module, the development of in silico models for toxicity testing will be discussed.
完成时间为 4 小时
10 个视频 （总计 119 分钟）, 4 个阅读材料, 2 个测验
完成时间为 3 小时
Module 3
This module will familiarize you with the Human Toxome Project run by Johns Hopkins University in collaboration with several university, industry, and research agencies. Omics technologies, their advantages and disadvantages, as well as concepts of Adverse Outcome Pathways (AOP) and Pathways of Toxicity (PoT) will be discussed.
完成时间为 3 小时
10 个视频 （总计 109 分钟）, 2 个阅读材料, 1 个测验
完成时间为 5 小时
Module 4
The first lesson in this module will explain the concept of read-across, why it is important for regulatory risk assessment, and how it can be implemented by industry in response to REACH legislation. The organotypic cultures lesson will teach you about existing in vitro cell-based models starting from simple monolayer cultures of cell lines and ending with complex combined organ-on-a-chip and human-on-a-chip approaches.
完成时间为 5 小时
18 个视频 （总计 185 分钟）, 3 个阅读材料, 2 个测验
完成时间为 2 小时
Module 5
This module will teach you the role of miRNA and epigenetics in toxicology and environmental health.
完成时间为 2 小时
6 个视频 （总计 41 分钟）, 1 个阅读材料, 1 个测验
审阅
- 5 stars79.72%
- 4 stars12.16%
- 3 stars5.40%
- 1 star2.70%
来自TOXICOLOGY 21: SCIENTIFIC APPLICATIONS的热门评论
由 SB 提供Mar 27, 2021
Helpful Course in Understanding Current trend in toxicological testings
由 I 提供May 25, 2020
one of the best course helps students & researcher about what are challenges faced in toxicology in 21 century and finds the routes to develop new routes and methods for toxicology tests
由 S 提供May 3, 2018
Very nicely designed course. The instructors offer an excellent and easy to understand overview of a range of promising Tox21 tools and approaches using good examples and illustrations.
由 PR 提供Sep 5, 2021
I am very happy and glad to part of your course.Thank you
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