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学生对 丹麦技术大学 提供的 Whole genome sequencing of bacterial genomes - tools and applications 的评价和反馈

4.6
886 个评分
241 条评论

课程概述

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

热门审阅

AP
Jul 19, 2020

Thank you very much for this course through which i learnt basic handling of bioinformatics tools and concepts of WGS. This will help me a lot while pursuing my PhD research work in my field.

MB
Jun 9, 2019

Excellent course with a wealth of information about tools and applications of whole genome sequencing. Presented in a very lucid and interesting manner, very crispy and simplified course.

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76 - Whole genome sequencing of bacterial genomes - tools and applications 的 100 个评论(共 242 个)

创建者 PC

Sep 25, 2019

A short but fun course to learn about the various tools and applications available for whole genome sequencing.

创建者 Viviane G

Aug 13, 2020

I have enjoyed the learning process during this course! Its very good for biological interested professionals.

创建者 Sanam P

Apr 15, 2020

Enjoyed this course. Now, I do have much idea in WGS. Thank you all the instructors for designing this course.

创建者 Carlos H C

Nov 19, 2017

A clear and very didactic course on the tools that DTU offers to analyze genomes. Thanks for the classes!

创建者 ALEXANDROS D

Jun 26, 2019

Very useful and helpful course to know how to interprete your results in different platforms and tools.

创建者 Parinda B

Jun 18, 2020

It was a great experience. I really enjoyed doing the course and hope tit will help me in the future

创建者 Suprim T

May 11, 2020

Although I have 5 starred the course, a more practical approach could be incorporated in the course.

创建者 Md. M A

May 24, 2020

Really excellent course. Must suggested for those who have interest in WGS(Whole Genome Sequencing)

创建者 Kathya A O

Jul 11, 2020

Definitely gained a lot more than i expected! It was very helpful and I would really recommend it.

创建者 Anushka J

Apr 16, 2020

the experience of learning this course was amazing. the faculties explained everything very well.

创建者 MUTSHIENE D E

Mar 29, 2019

Great and very insightful course. It really shed light on many aspects on whole genome sequencing

创建者 Josue D C C

Oct 3, 2018

Excelente curso, brinda una gran cantidad de herramientas muy útiles para realizar investigación.

创建者 Hamza A D

Nov 9, 2018

I like this course very much! The instructors were really helpful in getting their point across.

创建者 Mohammed Y

Aug 20, 2020

This was an awesome exposure. I would like to learn more about metagenomics in the next course.

创建者 Jaswandi

Jun 1, 2020

Excellent course with easy to understand explanation and illustration from the instructors.

创建者 Sonali S

Aug 2, 2019

Coursera gave me confidence and information about latest knowledge. Many thanks to coursera

创建者 Jana M

Dec 15, 2018

Great course, but very challenging. You need to be advanced in biology to do this course.

创建者 WAI K L

Nov 27, 2018

Great course that help student to understand the application for non computing scientist.

创建者 John A T L

Jun 4, 2020

It is an amazing course, very educational, clear, and helps to put concepts in practice.

创建者 Dwayne P

Sep 3, 2017

Excellent, had so much fun doing the course. Thank you DTU team, you guys are amazing.

创建者 Josep R C G

Oct 8, 2020

A very complete course about how to use the genomic tools freely available at the CGE

创建者 Gajanan T

Sep 25, 2020

Thank you so much, this course is very informative and helpful in my academic carrier

创建者 J K . S

Feb 11, 2018

FANTASTIC COURSE...!!!! HELPED ME TO DEVELOP INTEREST IN MOLECULAR BIOLOGY .

创建者 Manikandan M

Oct 16, 2017

GOOD ONE TO GET KNOWLEDGE ABOUT WHOLE GENOME SEQUENCING AND BACTERIAL SUB TYPING