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学生对 丹麦技术大学 提供的 Whole genome sequencing of bacterial genomes - tools and applications 的评价和反馈

4.6
956 个评分
255 条评论

课程概述

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

热门审阅

AP
Jul 19, 2020

Thank you very much for this course through which i learnt basic handling of bioinformatics tools and concepts of WGS. This will help me a lot while pursuing my PhD research work in my field.

MB
Jun 9, 2019

Excellent course with a wealth of information about tools and applications of whole genome sequencing. Presented in a very lucid and interesting manner, very crispy and simplified course.

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151 - Whole genome sequencing of bacterial genomes - tools and applications 的 175 个评论(共 255 个)

创建者 Ibrahim H

Nov 9, 2019

This lecuers exterimly useful.

创建者 1806071

Sep 8, 2019

Very very informative course

创建者 Pamela M

Apr 21, 2021

The best course about WGS!

创建者 Mayur M

Jun 25, 2020

Very Clear and informative

创建者 Alexandru B

Mar 25, 2018

very useful. thanks a lot.

创建者 Moayad M A

Aug 21, 2017

very easy and interactive

创建者 HARISH A 1

Jun 18, 2020

i had finally learned

it

创建者 Mark R

Jul 5, 2018

简单明了,适合初学者和做细菌分型溯源的生物学家

创建者 Verruchi G 1

Aug 15, 2020

ONE OF THE BEST COURSE

创建者 Hanan K M H

Jul 4, 2020

WONDERFUL >> THANK YOU

创建者 Paola D S

Jul 1, 2020

Useful, well planned!

创建者 Johanna M

Apr 24, 2020

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创建者 Mustafa R C

Jan 6, 2018

Very good, Thanks DTU

创建者 CHUKKA S K

Dec 2, 2020

very understandable

创建者 Arvind K

May 14, 2021

Very knowledgeable

创建者 Revathy B

May 26, 2020

really informative

创建者 Hajar F A

Apr 23, 2020

Really appreciate!

创建者 umashankar

Jun 3, 2021

Very nice content

创建者 Shanmukha A P

Jun 8, 2020

Excellent course

创建者 Christian A

Jun 6, 2020

Easy to follow

创建者 Bertram K

Aug 2, 2020

Great Course!

创建者 A A A E

Jan 8, 2019

applications

创建者 shuva s

Apr 9, 2018

Learnt a lot

创建者 Bavani L

Jun 4, 2020

Nice good

创建者 Abhinandan C

Nov 16, 2017

Great One