A two-part course lays down an understanding of the fundamental foundations of the structure of atoms and molecules, chemical bonds, intermolecular interactions. The course systematically reveals the relationship between the electronic structure of atoms and molecules, the periodic law of D.I. Mendeleev and the properties of substances and materials in various states of aggregation, modern achievements in the creation of various functional materials with desired properties, the foundations of the digital economy in the field of chemical sciences are considered.