It is also irritant to the eye, the respiratory irritant, the skin irritant.
The good news, it is not a carcinogen.
But it is a co-carcinogen.
It is promoting the carcinogenic effect of other substance which are applied at
the same time.
Has unclear mutagenicity findings, so damage to the genes.
And it also is producing embryonic malformations in essentially
any animal species tested.
Cat, dog, rat, mice, rabbit, and monkey data are very clear.
Aspirin is damaging the fetal development but not in humans.
89,000 pregnancies had been analysed that there's no evidence
of aspirin impacting on fetal development.
So you could say, it is quite unlikely to bring the subs like aspirin to the market
today, or we can be lucky that there was no regulatory toxicology 1897.
But I don't want to argue against regulation.
And I want to use the very same example.
This is an advertisement from Bayer from the turn of the last century,
where aspirin was advertised but there's also very interesting second product here
which is heroin, a sedative for coughs.