ModelingR ProgrammingMathematical ModelInfectious Diseases
您将学到的内容有
Construct valid mathematical models capturing the natural history of a given infectious disease.
Implement a mathematical model in R, calibrating it against epidemiological data in order to estimate key model parameters
Use a calibrated model to create model projections for different intervention scenarios
Explain the strengths and limitations of a mathematical model in relation to given research and policy questions
您将获得的技能
关于此 专项课程
11,348 次近期查看
Mathematical modelling is increasingly being used to support public health decision-making in the control of infectious diseases. This specialisation aims to introduce some fundamental concepts of mathematical modelling with all modelling conducted in the programming language R - a widely used application today.
The specialisation will suit you if you have a basic working knowledge of R, but would also like to learn the necessary basic coding skills to write simple mathematical models in this language. While no advanced mathematical skills are required, you should be familiar with ordinary differential equations, and how to interpret them. You'll receive clear instruction in the basic theory of infectious disease modelling alongside practical, hands-on experience of coding models in the programming language R.
可分享的证书
完成后获得证书
100% 在线课程
立即开始，按照自己的计划学习。
灵活的计划
设置并保持灵活的截止日期。
中级
需要一些相关领域经验。需要一些相关经验。
完成时间大约为3 个月
建议 5 小时/周
英语（English）
字幕：英语（English）
可分享的证书
完成后获得证书
100% 在线课程
立即开始，按照自己的计划学习。
灵活的计划
设置并保持灵活的截止日期。
中级
需要一些相关领域经验。需要一些相关经验。
完成时间大约为3 个月
建议 5 小时/周
英语（English）
字幕：英语（English）
此专项课程包含 3 门课程
Developing the SIR Model
128 个评分
Compartmental modelling is a cornerstone of mathematical modelling of infectious diseases and this course will introduce some of the basic concepts in building compartmental models, including how to interpret and represent rates, durations and proportions. You'll learn to place the mathematics to one side and concentrate on gaining intuition into the behaviour of a simple epidemic, and be introduced to further basic concepts of infectious disease epidemiology, such as the basic reproduction number (R0) and its implications for infectious disease dynamics. To express the mathematical underpinnings of the basic drivers that you study, you'll use the simple SIR model, which, in turn, will help you examine different scenarios for reproduction numbers. Susceptibility to infection is the fuel for an infectious disease, so understanding the dynamics of susceptibility can offer important insights into epidemic dynamics, as well as priorities for control.
Interventions and Calibration
25 个评分
This course covers approaches for modelling treatment of infectious disease, as well as for modelling vaccination. Building on the SIR model, you will learn how to incorporate additional compartments to represent the effects of interventions, such the effect of vaccination in reducing susceptibility. You will learn about ‘leaky’ vaccines and how to model them, as well as different types of vaccine and treatment effects. It is important to consider basic relationships between models and data, so, using the basic SIR model you have developed in course 1, you will calibrate this model to epidemic data. Performing such a calibration by hand will help you gain an understanding of how model parameters can be adjusted in order to capture real-world data. Lastly in this course, you will learn about two simple approaches to computer-based model calibration - the least-squares approach and the maximum-likelihood approach; you will perform model calibrations under each of these approaches in R.
Building on the SIR Model
9 个评分
The other two courses in this specialisation require you to perform deterministic modelling - in other words, the epidemic outcome is predictable as all parameters are fully known. However, this course delves into the many cases – especially in the early stages of an epidemic – where chance events can be influential in the future of an epidemic. So, you'll be introduced to some examples of such ‘stochasticity’, as well as simple approaches to modelling these epidemics using R. You will examine how to model infections for which such ‘population structure’ plays an important role in the transmission dynamics, and will learn some of the basic approaches to modelling vector-borne diseases, including the Ross-McDonald Model.
提供方
伦敦帝国学院
Imperial College London is a world top ten university with an international reputation for excellence in science, engineering, medicine and business. located in the heart of London. Imperial is a multidisciplinary space for education, research, translation and commercialisation, harnessing science and innovation to tackle global challenges.
立即开始攻读硕士学位
此 专项课程 隶属于 伦敦帝国学院 提供的 100% 在线 Global Master of Public Health。如果您被录取参加全部课程，您的课程将计入您的学位学习进程。
常见问题
完成专项课程后我会获得大学学分吗？
此专项课程不提供大学学分，但部分大学可能会选择接受专项课程证书作为学分。查看您的合作院校，了解详情。Coursera 上的在线学位和 Mastertrack™ 证书提供获得大学学分的机会。
Can I just enroll in a single course?
如果订阅，您可以获得 7 天免费试听，在此期间，您可以取消课程，无需支付任何罚金。在此之后，我们不会退款，但您可以随时取消订阅。请阅读我们完整的退款政策。
我可以只注册一门课程吗？
可以！点击您感兴趣的课程卡开始注册即可。注册并完成课程后，您可以获得可共享的证书，或者您也可以旁听该课程免费查看课程资料。如果您订阅的课程是某专项课程的一部分，系统会自动为您订阅完整的专项课程。访问您的学生面板，跟踪您的进度。
Can I take the course for free?
是的，Coursera 可以为无法承担费用的学生提供助学金。通过点击左侧“注册”按钮下的“助学金”链接可以申请助学金。您可以根据屏幕提示完成申请，申请获批后会收到通知。您需要针对专项课程中的每一门课程完成上述步骤，包括毕业项目。了解更多。
我可以免费学习课程吗？
完成注册课程后，您可以学习专项课程中的所有课程，并且完成作业后可以获得证书。如果您只想阅读和查看课程内容，可以免费旁听该课程。如果您无法承担课程费用，可以申请助学金。
此课程是 100% 在线学习吗？是否需要现场参加课程？
此课程完全在线学习，无需到教室现场上课。您可以通过网络或移动设备随时随地访问课程视频、阅读材料和作业。
How long does it take to complete the Specialization?
Approximately 4 hours a week for 3 to 4 months
完成专项课程需要多长时间？
We recommend taking the courses in the order in which they are displayed on the main page of the Specialization
Will I earn university credit for completing the Specialization?
No. Participating in this specialisation will not earn you university credit.
还有其他问题吗？请访问 学生帮助中心。
