课程信息
4.7
662 个评分
150 个审阅
100% 在线

100% 在线

立即开始,按照自己的计划学习。
可灵活调整截止日期

可灵活调整截止日期

根据您的日程表重置截止日期。
初级

初级

完成时间(小时)

完成时间大约为13 小时

建议:12-18 hours videos and labs...
可选语言

英语(English)

字幕:英语(English)

您将获得的技能

Genetic AnalysisBioinformatics AnalysisEvolutionComparative Genomics
100% 在线

100% 在线

立即开始,按照自己的计划学习。
可灵活调整截止日期

可灵活调整截止日期

根据您的日程表重置截止日期。
初级

初级

完成时间(小时)

完成时间大约为13 小时

建议:12-18 hours videos and labs...
可选语言

英语(English)

字幕:英语(English)

教学大纲 - 您将从这门课程中学到什么

1
完成时间(小时)
完成时间为 3 小时

NCBI/Blast I

In this module we'll be exploring the amazing resources available at NCBI, the National Centre for Biotechnology Information, run by the National Library of Medicine in the USA. We'll also be doing a Blast search to find similar sequences in the enormous NR sequence database. We can use similar sequences to infer homology, which is the primary predictor of gene or protein function. ...
Reading
4 个视频 (总计 52 分钟), 4 个阅读材料, 1 个测验
Video4 个视频
Lecture25分钟
Lab Discussion24分钟
Summary
Reading4 个阅读材料
Acknowledgements10分钟
Course Logistics10分钟
Lecture Materials10分钟
Lab 1 -- Exploring NCBI30分钟
Quiz1 个练习
Lab 1 Quiz6分钟
2
完成时间(小时)
完成时间为 3 小时

Blast II/Comparative Genomics

In this module we'll continue exploring the incredible resources available at NCBI, the National Centre for Biotechnology Information. We will be performing several different kinds of Blast searches: BlastP, PSI-Blast, and Translated Blast. We can use similar sequences identified by such methods to infer homology, which is the primary predictor of gene or protein function. We'll also be comparing parts of the genomes of a couple of different species, to see how similar they are....
Reading
4 个视频 (总计 58 分钟), 2 个阅读材料, 1 个测验
Video4 个视频
Lecture32分钟
Lab Discussion23分钟
Summary
Reading2 个阅读材料
Lecture Materials10分钟
Lab 2 -- Advanced Blast and Comparative Genomics30分钟
Quiz1 个练习
Lab 2 Quiz6分钟
3
完成时间(小时)
完成时间为 2 小时

Multiple Sequence Alignments

In this module we'll be doing multiple sequence alignments with Clustal (as implemented in MEGA), DiAlign, and MAFFT. Multiple sequences alignments can tell you where in a sequence the conserved and variable regions are, which is important for understanding the biology of the sequences under investigation. It also has practical applications, such as being able to design PCR primers that will amplify sequences from a number of different species, for example....
Reading
4 个视频 (总计 42 分钟), 2 个阅读材料, 1 个测验
Video4 个视频
Lecture23分钟
Lab Discussion16分钟
Summary
Reading2 个阅读材料
Lecture Materials10分钟
Lab 3 -- Multiple Sequence Alignment30分钟
Quiz1 个练习
Lab 3 Quiz6分钟
4
完成时间(小时)
完成时间为 10 分钟

Review: NCBI/Blast I, Blast II/Comparative Genetics, and Multiple Sequence Alignments

...
Reading
1 个测验
Quiz1 个练习
Quiz: Modules 1-310分钟
4.7
150 个审阅Chevron Right
职业方向

25%

完成这些课程后已开始新的职业生涯
工作福利

31%

通过此课程获得实实在在的工作福利
职业晋升

21%

加薪或升职

热门审阅

创建者 EDApr 27th 2017

Great course. All lectures provide a biological context for the tools you learn in the labs. The labs themselves provide a great introduction to the many tools available for bioinformatic analysis.

创建者 FJFeb 6th 2017

The videos were very clear on how to use various bioinformatic tools. I found no difficulty in understanding them. Really enjoyed the course. Looking forward to the next part of this course!

讲师

Avatar

Nicholas James Provart

Professor
Cell & Systems Biology

关于 多伦多大学

Established in 1827, the University of Toronto is one of the world’s leading universities, renowned for its excellence in teaching, research, innovation and entrepreneurship, as well as its impact on economic prosperity and social well-being around the globe. ...

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