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学生对 丹麦技术大学 提供的 Whole genome sequencing of bacterial genomes - tools and applications 的评价和反馈

4.6
281 个评分
72 个审阅

课程概述

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

热门审阅

MB

Jun 10, 2019

Excellent course with a wealth of information about tools and applications of whole genome sequencing. Presented in a very lucid and interesting manner, very crispy and simplified course.

XL

Jun 30, 2019

The course is using cutting-edge genome sequencing technology and the authentic software to showcasing the applications and tools of genome sequencing. It is a great chance to learn it.

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26 - Whole genome sequencing of bacterial genomes - tools and applications 的 50 个评论(共 72 个)

创建者 Heba M M

Oct 14, 2017

Good course, with amazing hands-on practice. Thanks it was really helpful.

创建者 sandeep K

May 18, 2018

The contents of the course were really very good and with loads of knowledge. Thank you very much for improving my knowledge in this area.

创建者 Sarah A

Mar 12, 2018

one of the best courses ever i learned so many things in a short period. looking forward to your next course.

Thanks

创建者 Dwayne P

Sep 03, 2017

Excellent, had so much fun doing the course. Thank you DTU team, you guys are amazing.

创建者 Manikandan M

Oct 16, 2017

GOOD ONE TO GET KNOWLEDGE ABOUT WHOLE GENOME SEQUENCING AND BACTERIAL SUB TYPING

创建者 Adithya A

May 23, 2018

EXCELLENT COURSE GOOD FOR ANY ONE WHO HAS A BASIC KNOWLEDGE ON GENETICS

创建者 Pham T T T

Sep 17, 2017

Thank you great team from DTU, I get to understand NGS via your detailed explanation and useful demonstration as well as example exercise. Cheers

创建者 俞骅

Jul 05, 2018

简单明了,适合初学者和做细菌分型溯源的生物学家

创建者 Vanessa C d C L

Jan 14, 2018

This is a very interesting course, it's practical and simple to follow and I've learned a lot about whole genome sequencing and its techniques.

创建者 julio a a j

Mar 15, 2018

excelente curso me sirvió mucho para mi phD, gracias!

创建者 Opeyemi U L

Feb 02, 2018

The module was easy to follow and the class exercises made it very easy to understand. I will highly recommend this course to microbiology students especially the ones without prior knowledge of basic bioinformatics for epidemiological study of bacterial infections

创建者 J K . S

Feb 11, 2018

FANTASTIC COURSE...!!!! HELPED ME TO DEVELOP INTEREST IN MOLECULAR BIOLOGY .

创建者 shuva s

Apr 09, 2018

Learnt a lot

创建者 Jolanta G

Aug 28, 2017

Thank you for the excellent course. It was very interesting to try upload genome and use various tools for identification of the pathogens and resistance mechanisms.Very useful information and excellent excercises. Good luck!

创建者 Abhinandan C

Nov 16, 2017

Great One

创建者 Pitithat p

Aug 29, 2017

Very nice comprehensive course. Looking forward to join the metagenomic course

创建者 Ana V U B

Dec 17, 2017

I loved the course. I lerned how to use different tools to understant a DNA information, with a lot of practical exercises. I can wait the course of metagenomics.

创建者 Gourab D

Aug 20, 2017

Madam/Sir,

I am a Computer Science Engineer, I am doing research in University of Calcutta in Machine Learning. I have some interest in Bioinformatics. It is not possible for me to grab all the aspect in that subject. So, I am grabbing it in scattered way. The course I have completed in "DTU" has captured a complete different aspect which I haven't seen before. The most important things is that it is a very neat and clean course with a specific direction. All the labs which I have performed here has been well taught in various videos. Though it is not possible for me to understand every parts of all the videos but still it gives me enough knowledge to complete the practicals. I hope it will help me in future run.

I would like to specify just one problem related with the course. Every course in Coursera has "Discussion Forum" corresponding to every week, which I have found missing, as it solves lot of dynamic problem in each week's tutorial. I am sorry if "Discussion Forum" is already there and I have ignored that.

Thanks You very much,

Gourab Das

创建者 Kris s

Dec 08, 2017

Genuinly seems fun.

Keep it up Team at TUD

创建者 Erica Y

Oct 01, 2018

Good course for a beginner. Generally, help me understand whole genome sequencing of bacteria. Will follow other course that they have provide.

创建者 Mohamed E

Jul 28, 2018

Not to mention, the power of the tools illustrated in this course, I just wanna mention that I am senior student in bioinformatics bachelor degree and Dr. Pimlapas Leekitcharoenphon is by far the best instructor I have ever come across in the field till now. Thank you.

创建者 Syed H A

Jun 12, 2019

The Design, of course, is best as per researcher requirement.

创建者 ALEXANDROS D

Jun 26, 2019

Very useful and helpful course to know how to interprete your results in different platforms and tools.

创建者 Mirza M V B

Jun 10, 2019

Excellent course with a wealth of information about tools and applications of whole genome sequencing. Presented in a very lucid and interesting manner, very crispy and simplified course.

创建者 AKM F H

Jun 10, 2019

This is a really good course for beginners as it explained the use of some fantastic web-based tools to detect bacterial ST, resistance, plasmid, MLST, and phylogeny. I have learned a lot of new techniques to analyze the whole genome of a bacterium. Thank you for giving me the opportunity.