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学生对 丹麦技术大学 提供的 Whole genome sequencing of bacterial genomes - tools and applications 的评价和反馈

4.6
350 个评分
88 个审阅

课程概述

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

热门审阅

MB

Jun 10, 2019

Excellent course with a wealth of information about tools and applications of whole genome sequencing. Presented in a very lucid and interesting manner, very crispy and simplified course.

XL

Jun 30, 2019

The course is using cutting-edge genome sequencing technology and the authentic software to showcasing the applications and tools of genome sequencing. It is a great chance to learn it.

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26 - Whole genome sequencing of bacterial genomes - tools and applications 的 50 个评论(共 88 个)

创建者 Dwayne P

Sep 03, 2017

Excellent, had so much fun doing the course. Thank you DTU team, you guys are amazing.

创建者 julio a a j

Mar 15, 2018

excelente curso me sirvió mucho para mi phD, gracias!

创建者 J K . S

Feb 11, 2018

FANTASTIC COURSE...!!!! HELPED ME TO DEVELOP INTEREST IN MOLECULAR BIOLOGY .

创建者 shuva s

Apr 09, 2018

Learnt a lot

创建者 Jolanta G

Aug 28, 2017

Thank you for the excellent course. It was very interesting to try upload genome and use various tools for identification of the pathogens and resistance mechanisms.Very useful information and excellent excercises. Good luck!

创建者 Abhinandan C

Nov 16, 2017

Great One

创建者 Valeria O M

Jun 03, 2018

Me gustaron los video que van directo al fundamento de cada herramienta, y lo mejor es que el curso también se enfoca en la aplicación de lo enseñado. Gracias

创建者 Bologa A M

Mar 25, 2018

very useful. thanks a lot.

创建者 Ana V U B

Dec 17, 2017

I loved the course. I lerned how to use different tools to understant a DNA information, with a lot of practical exercises. I can wait the course of metagenomics.

创建者 Kris s

Dec 08, 2017

Genuinly seems fun.

Keep it up Team at TUD

创建者 Nimat U

Oct 20, 2018

Thank you very much to all the team of DTU for organizing this course and made it easy for every student/researcher to analyze genomic sequence data. This course was very helpful to me and I appreciate Dr. Shinny for her excellent teaching methodology.

创建者 Ahmed E A e

Oct 31, 2018

It isa fantastic course to spend your time

创建者 Hamza A D

Nov 09, 2018

I like this course very much! The instructors were really helpful in getting their point across.

创建者 Audrey V

Nov 21, 2018

I only just begin taking part in it and all I can say is I am enjoying it even though I am a bit behind schedule and my first attempt was 60%, I will try again and aim high with better understanding. Thank you for the opportunity and the financial aid that was approved for me to attend the course. I am determined to do my best. What I also like is the clear teaching or lecturing manner of all the presenters of the course.

创建者 WAI K L

Nov 27, 2018

Great course that help student to understand the application for non computing scientist.

创建者 Josue D C C

Oct 03, 2018

Excelente curso, brinda una gran cantidad de herramientas muy útiles para realizar investigación.

创建者 ALEXANDROS D

Jun 26, 2019

Very useful and helpful course to know how to interprete your results in different platforms and tools.

创建者 Adil M

Jul 01, 2019

It was highly informative and interesting. I enjoyed alot

创建者 Xiangyang L

Jun 30, 2019

The course is using cutting-edge genome sequencing technology and the authentic software to showcasing the applications and tools of genome sequencing. It is a great chance to learn it.

创建者 AKM F H

Jun 10, 2019

This is a really good course for beginners as it explained the use of some fantastic web-based tools to detect bacterial ST, resistance, plasmid, MLST, and phylogeny. I have learned a lot of new techniques to analyze the whole genome of a bacterium. Thank you for giving me the opportunity.

创建者 Syed H A

Jun 12, 2019

The Design, of course, is best as per researcher requirement.

创建者 SONALI S

Aug 02, 2019

Coursera gave me confidence and information about latest knowledge. Many thanks to coursera

创建者 Jaya S

Nov 25, 2019

Great course. Excellent for research.

创建者 1806071

Sep 08, 2019

Very very informative course

创建者 Kira K

Dec 04, 2018

This is a great class presenting a user-friendly web tool CGE pipeline that is ready to help all researches with their bioinformatics data. It can even build phylogenetic trees!

And I loved a small detective game at the end of the course when we needed to process unknown bacteria sequences to see if it was a real outbreak and what antibiotics were able to stop it!

A lot of thanks to the team!