课程信息
4.8
42 ratings
10 reviews
The objective of this course is to give students the most up-to-date information on the biological, personal, and societal relevance of sleep. Personal relevance is emphasized by the fact that the single best predictor of daytime performance is the quality of the previous night's sleep. The brain actively generates sleep, and the first section of the course is an overview of the neurobiological basis of sleep control. The course provides cellular-level understanding of how sleep deprivation, jet lag, and substances such as alcohol, ,caffeine, and nicotine alter sleep and wakefulness. The second section of the course covers sleep-dependent changes in physiology and sleep disorders medicine. Particular emphasis will be placed on disorders of excessive sleepiness, insomnia, and sleep-dependent changes in autonomic control. Chronic sleep deprivation impairs immune function and may promote obesity. Deaths due to all causes are most frequent between 4:00 and 6:00 a.m., and this second section of the class highlights the relevance of sleep for preventive medicine. The societal relevance of sleep will be considered in the final section of the class. In an increasingly complex and technologically oriented society, operator-error by one individual can have a disastrous negative impact on public health and safety. Fatigue-related performance decrements are known to have contributed as causal factors to nuclear power plant failures, transportation disasters, and medical errors....
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100% 在线课程

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Beginner Level

初级

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建议:5 hours/week

完成时间大约为19 小时
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English

字幕:English
Globe

100% 在线课程

立即开始,按照自己的计划学习。
Calendar

可灵活调整截止日期

根据您的日程表重置截止日期。
Beginner Level

初级

Clock

建议:5 hours/week

完成时间大约为19 小时
Comment Dots

English

字幕:English

教学大纲 - 您将从这门课程中学到什么

1

章节
Clock
完成时间为 2 小时

Unit 01 - Neurobiology Section: Course Introduction & Neurobiology of Sleep and Wakefulness (Part One) - (Standard Track & Honors Track)

This unit begins with a Course Overview video from Ralph Lydic, Ph.D., followed by the first portion of the Neurobiology of Sleep and Wakefulness lecture, delivered by Helen Baghdoyan, Ph.D. PLEASE NOTE: Only the Course Overview video, and the Getting Started and Syllabus readings are required for students who have chosen to engage in the Standard Track portion of the course content. Standard track students may also bypass all content in units 2, 3, and 4, and instead move directly to unit 5 after viewing the Course Overview video....
Reading
6 个视频(共 93 分钟), 4 个阅读材料, 1 个测验
Video6 个视频
02.01 - Learning Points14分钟
02.02 - Defining Behavioral States8分钟
02.03 - Historical Overview: Brainstem & Forebrain17分钟
02.04 - Wake & REM: Monoamines17分钟
02.05 - Wake & REM: Acetylcholine17分钟
Reading4 个阅读材料
Getting Started10分钟
Syllabus10分钟
Help Us Learn More About You!10分钟
Lesson 2 Orientation10分钟
Quiz1 个练习
Did you Complete Lesson 2?2分钟

2

章节
Clock
完成时间为 2 小时

Unit 02 - Neurobiology Section: Neurobiology of Sleep and Wakefulness (Part Two) - (Honors Track)

Unit 2 continues the lecture from Helen Baghdoyan, Ph.D. on the Neurobiology of Sleep and Wakefulness. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification....
Reading
5 个视频(共 73 分钟), 2 个测验
Video5 个视频
02.07: Wake & REM: Orexin17分钟
02.08: NREM: GABA14分钟
02.09: NREM: Adenosine 11分钟
02:10: Summary12分钟
Quiz2 个练习
Did you complete Lesson 03?2分钟
Unit 02 Honors Track Quiz - Neurobiology of Sleep and Wakefulness30分钟

3

章节
Clock
完成时间为 1 小时

Unit 03 - Neurobiology: Mathematical Modeling of Sleep-Wake Regulation - (Honors Track)

Unit 3 continues the Neurobiology section of the content with a lecture from Victoria Booth, Ph.D. on the Mathematical Modeling of Sleep-Wake Regulation. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification....
Reading
10 个视频(共 67 分钟), 1 个阅读材料, 2 个测验
Video10 个视频
03.02 - Two Process Model 5分钟
03.03 - Sleep-Wake Flip-Flop Model5分钟
03.04 - Reciprocal Interaction Model 12分钟
03.05 - REM Sleep Flip-Flop Model4分钟
03.06 - Features for an Ideal Model of Sleep-Wake Regulation7分钟
03.07 - Introduction to Mechanistic Models of Sleep-Wake Regulation 3分钟
03.08 - Diniz Benh & Booth Model - Part I9分钟
03.09 - Diniz Benh & Booth Model - Part II 14分钟
03.10 - Conclusion 1分钟
Reading1 个阅读材料
Unit 03 Orientation10分钟
Quiz2 个练习
Did you Complete Lesson 5?2分钟
Unit 03 Quiz - Mathematical Modeling of Sleep-Wake Regulation10分钟

4

章节
Clock
完成时间为 1 小时

Unit 04 - Neurobiology: Molecular Biology and Genetics of Sleep - (Honors Track)

Unit 4 closes out the Neurobiology section with a lecture from Chiara Cirelli, Ph.D. on Molecular Biology and the Genetics of Sleep. PLEASE NOTE: This content is only required for students who have chosen to pursue the Honors Track certification....
Reading
6 个视频(共 52 分钟), 2 个测验
Video6 个视频
04.02 - Wake Genes that are Associated with Energy Metabolism 7分钟
04.03 - Synaptic Plasticity is Genetically Modulated 7分钟
04.04 - Brain Glial Cells Influence States of Sleep and Wakefulness 9分钟
04.05 - Genetic Modulation of Human Sleep Phenotypes 8分钟
04.06 - Conclusion 11分钟
Quiz2 个练习
Did you complete Lesson 7?2分钟
Unit 04 Quiz - Molecular Biology and Genetics of Sleep10分钟
4.8

热门审阅

创建者 JQJan 3rd 2018

Excellent course! A great review on stuff I should have remembered but of course have forgotten as I've aged. My thanks to those organizing and teaching the course! Dr Quincy

创建者 DFFeb 19th 2018

I thoroughly enjoyed this course and look forward to continuing my education on the subject.

讲师

Ralph Lydic, Ph.D.

Professor Emeritus, Molecular and Integrative Physiology, Professor Emeritus, Anesthesiology
University of Michigan Medical School

Helen Baghdoyan, Ph.D.

Professor Emeritus, Anesthesiology, Professor Emeritus, Pharmacology, Professor of Psychiatry
University of Michigan Medical School

关于 University of Michigan

The mission of the University of Michigan is to serve the people of Michigan and the world through preeminence in creating, communicating, preserving and applying knowledge, art, and academic values, and in developing leaders and citizens who will challenge the present and enrich the future....

常见问题

  • Once you enroll for a Certificate, you’ll have access to all videos, quizzes, and programming assignments (if applicable). Peer review assignments can only be submitted and reviewed once your session has begun. If you choose to explore the course without purchasing, you may not be able to access certain assignments.

  • When you purchase a Certificate you get access to all course materials, including graded assignments. Upon completing the course, your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile. If you only want to read and view the course content, you can audit the course for free.

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