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学生对 墨尔本大学 提供的 基因表达的表观遗传调控 的评价和反馈

4.8
518 个评分
134 个审阅

课程概述

While the human genome sequence has transformed our understanding of human biology, it isn’t just the sequence of your DNA that matters, but also how you use it! How are some genes activated and others are silenced? How is this controlled? The answer is epigenetics. Epigenetics has been a hot topic for research over the past decade as it has become clear that aberrant epigenetic control contributes to disease (particularly to cancer). Epigenetic alterations are heritable through cell division, and in some instances are able to behave similarly to mutations in terms of their stability. Importantly, unlike genetic mutations, epigenetic modifications are reversible and therefore have the potential to be manipulated therapeutically. It has also become clear in recent years that epigenetic modifications are sensitive to the environment (for example diet), which has sparked a large amount of public debate and research. This course will give an introduction to the fundamentals of epigenetic control. We will examine epigenetic phenomena that are manifestations of epigenetic control in several organisms, with a focus on mammals. We will examine the interplay between epigenetic control and the environment and finally the role of aberrant epigenetic control in disease. All necessary information will be covered in the lectures, and recommended and required readings will be provided. There are no additional required texts for this course. For those interested, additional information can be obtained in the following textbook. Epigenetics. Allis, Jenuwein, Reinberg and Caparros. Cold Spring Harbour Laboratory Press. ISBN-13: 978-0879697242 | Edition: 1...

热门审阅

MM

Oct 02, 2018

This was an excellent course. All the material was well presented and the explanation of the sometimes complex subject matter was clear and understandable. Thank you for an great learning experience.

DS

Aug 25, 2018

This is an excellent course that introduces you to fundamental knowledge of several hot topics in the field of epigenetics. Dr. Blewitt herself studies X inactivation, and I learned so much!

筛选依据:

1 - 基因表达的表观遗传调控 的 25 个评论(共 130 个)

创建者 Ismael V M

Jul 24, 2019

Fantastic course excelente teacher thanks.

创建者 Apoorva S

Jul 21, 2019

A great learning platform. This was my first ever course on coursera and I've thoroughly enjoyed it. A big thank you to Dr. Marnie Blewitt for helping us learn in a fun way!

创建者 EBENEZER W

Jul 24, 2019

Definitely an enchanting learning experience. This course expresses thoughts on epigenetics and how it could be the key to solve menacing threats such as cancer. It starts with a brief history and remarkable discoveries by scientists, followed by its mechanism, case studies in animal models, cohort studies, and eventually its implementation in cancer therapy. It is very intriguing filled with quizzes, learning resources (podcasts, debates, research findings, interviews, and newspaper articles) and not to mention the ever-growing learning community. Highly recommended for aspirants of biology and those who want to understand life better. I am grateful to Dr. Marnie Blewitt, the curator, Ms. Natasha Jansz, the moderator, and her colleagues and also the University of Melbourne for an excellent journey of learning.

创建者 HanuRam

Dec 18, 2016

A quintessential course for Genetics students all over the world. Very nicely prepared and elucidated by Dr. Marnie Blewitt .

Many many thanks to Dr. Marnie Blewitt & Coursera team.

创建者 Narendra v

Feb 23, 2019

Its really a fascinating course to learn epigenetics, all classes and materials were really helpful

创建者 Mohammad K

Feb 27, 2019

Great and Very informative Course

创建者 Neelam F

Mar 01, 2019

it was an excellent course and worth spending time on.

创建者 Donald B

Mar 20, 2019

Best cousera I have taken. Extremely well done.

创建者 Afolake A

Mar 19, 2019

A very good course.

创建者 Paul S

Mar 30, 2019

Well organized and thought out. Developed the concepts well with clear examples from literature. Gave an understanding of the state of the field and where there are things that still need to be worked out.

创建者 Todor T G

Aug 07, 2017

One of the best course on Coursera on this topic for experts and not so. Thanks a lot and I'll be glad to see follow up on the subject.

创建者 Philip B P J

Apr 21, 2016

Very well done.

创建者 Marija R

Dec 24, 2016

An interesting course delivered in an excellent manner, with a challenging material being explained in a way that is easy to grasp.

创建者 Blair O

Jun 11, 2018

Excellent detail. Great delivery

创建者 Claudia B

Mar 31, 2016

What can I say? An extremely complete course, very resourceful, dynamic and with great quality content from reliable sources. If you are interested in genetics, you will love this take on epigenetics; definitely worth it.

创建者 Pedro T

Oct 09, 2016

It's pretty good :)

创建者 Ana C d S L

May 29, 2017

I strongly recommend this course, I learned a lot more than I expected to learn.

创建者 Bettina H

May 02, 2017

The course was great! I did not know much about epigenetics beforehand and now I feel like I could have an informed conversation. My curiosity was awakend

创建者 Chrissy - U

May 20, 2016

This was a wonderful course and I enjoyed it very much.

创建者 Julius K K

Sep 15, 2017

Clear to understand. Very informative. Thank you.

创建者 Ilir S

Dec 01, 2017

Awesome

创建者 Andrew E M

Dec 13, 2016

A great course! I certainly learnt a lot. Please note, that if you haven't studied a scientific course before, then I think you would find this course too challenging.

创建者 susan c

Jan 05, 2018

Fantastic! Incredibly informative.

I have been so busy- but i am always drawn back!

创建者 Amit K

Aug 01, 2017

Excellent course. Thoughtfully put together, very clear teaching.

创建者 Simone E G

Jun 05, 2016

This course is brilliant. It presents a complicated topic with some details, taking non-experts in Biology, like me, to a good understanding. It is worth remembering the main elements in the course from time to time, so I am retaking this course (at least the videos) to refresh my memory. Wonderful course. I truly recommend it.