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Design and Interpretation of Clinical Trials, Johns Hopkins University

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211 个审阅

课程信息

Clinical trials are experiments designed to evaluate new interventions to prevent or treat disease in humans. The interventions evaluated can be drugs, devices (e.g., hearing aid), surgeries, behavioral interventions (e.g., smoking cessation program), community health programs (e.g. cancer screening programs) or health delivery systems (e.g., special care units for hospital admissions). We consider clinical trials experiments because the investigators rather than the patients or their doctors select the treatment the patients receive. Results from randomized clinical trials are usually considered the highest level of evidence for determining whether a treatment is effective because trials incorporates features to ensure that evaluation of the benefits and risks of treatments are objective and unbiased. The FDA requires that drugs or biologics (e.g., vaccines) are shown to be effective in clinical trials before they can be sold in the US. The course will explain the basic principles for design of randomized clinical trials and how they should be reported. In the first part of the course, students will be introduced to terminology used in clinical trials and the several common designs used for clinical trials, such as parallel and cross-over designs. We will also explain some of the mechanics of clinical trials, like randomization and blinding of treatment. In the second half of the course, we will explain how clinical trials are analyzed and interpreted. Finally, we will review the essential ethical consideration involved in conducting experiments on people....

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创建者 TS

Jul 04, 2018

High quality course ! covering important areas and detailed lectures, more and better than a mere introduction. Congrats ! My only regret : I'd have liked to hear more about NI and equivalence trials

创建者 AM

Mar 20, 2016

This course is well-designed, well-paced and well-structured. The study examples described in this course really help you understand the importance of design and interpretation of clinical trials.

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204 个审阅

创建者 Rodrigo Py Gonçalves Barreto

Dec 11, 2018

Amazing course. They discuss basic principles and provide some insights about complex ones too. I'm loving it! Thanks for setting up this course.

创建者 Lara Vinuesa Galán

Dec 07, 2018

A very informative and interesting course. Despite the complexity of some issues, they manage to explain them in an understandable way. Thank you!

创建者 Mary Catherine Valencia

Dec 03, 2018

A great course for people working in the Clinical Research industry! I definitely recommend!

创建者 João Paulo Jordão Pontes

Nov 18, 2018

I think that the course should provide a written material in order to deepen the learning process.

创建者 Roberta Bossoni

Nov 02, 2018

A very good course: useful information explained in a clear and simple way.

创建者 RENE CASTREJON MORALES

Oct 21, 2018

el curso es excelente

创建者 FERNANDO CAMACHO-PALMA

Sep 30, 2018

It was amagazin

创建者 shaurya deep bajwa

Sep 10, 2018

An amazing course especially for professionals who work in clinical research operations. Very knowledgeable and interesting !

创建者 Evgeny Samoylov

Sep 04, 2018

This is a very good course to form a broad knowledge in clinical trial design

创建者 Zhanwu Cui

Aug 23, 2018

This is a great course!